Impaired microcirculation can result in a lack of energy in cells due to insufficient supply and removal processes. Initially, this leads to reduced performance and later to malfunctioning of the affected cells. If many cells in an organ or tissue are affected, corresponding symptoms will occur, which can then be defined as a disease. Cells lacking energy cannot function fully. Most cells have a specific lifespan after which they are renewed. Cells with insufficient energy die earlier. Our white blood cells—and thus the effectiveness of our immune system—are also directly dependent on microcirculation and the energy status of these cells.